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/Pg 7 0 R /K [10] >> endobj 221 0 obj << /Type /StructElem /S /H3 /P 23 0 R /T (EMULSEO - World Cancer Day, february 2024) /E (EMULSEO - World Cancer Day, february 2024) /Pg 7 0 R /K [4] >> endobj 222 0 obj << /Type /StructElem /S /H3 /P 23 0 R /T (1/2) /E (1/2) /Pg 7 0 R /K [6] >> endobj 223 0 obj << /Type /StructElem /S /Figure /P 24 0 R /Pg 8 0 R >> endobj 224 0 obj << /Type /StructElem /S /H1 /P 24 0 R /T (WORLD CANCER DAY 2024, FEBRUARY 4) /E (WORLD CANCER DAY 2024, FEBRUARY 4) /Pg 8 0 R /K [5] >> endobj 225 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText /Pg 8 0 R /K [12] >> endobj 226 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText /Pg 8 0 R /K [13] >> endobj 227 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText (In order to accurately mimic cancer tumors, 3D models like MCTSs play a critical role. Creating these tumor spheroids is crucial for anticancer treatment research, as they enable the characterization of various anticancer treatments. Droplet-based microfluidics allows a high-throughput generation of uniform spheroids that can be automated, and thus address the limitations of conventional methods for the generation of tumor spheroids.) /Pg 8 0 R /K [14] >> endobj 228 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText ([1] Froehlich K, Haeger JD, Heger J, Pastuschek J, Photini SM, Yan Y, et al. Generation of multicellular breast cancer tumor spheroids: Comparison of different protocols. J Mammary Gland Biol Neoplasia, 2016, 21, 89-98.) /Pg 8 0 R /K [7] >> endobj 229 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText ([2] Lee, S.I.; Choi, Y.Y.; Kang, S.G.; Kim, T.H.; Choi, J.W.; Kim, Y.J.; Kim, T.-H.; Kang, T.; Chung, B.G. 3D Multicellular Tumor Spheroids in a Microfluidic Droplet System for Investigation of Drug Resistance. Polymers, 2022, 14, 3752.) /Pg 8 0 R /K [8] >> endobj 230 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText ([3] Parent C., Raj Melayil K., Zhou Y., Aubert V., Surdez D., Delattre O., Wilhelm C., Viovy JL. Simple droplet microfluidics platform for drug screening on cancer spheroids. Lab Chip, 2023, 23, 5139-5150.) /Pg 8 0 R /K [9] >> endobj 231 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText ([4] Dimitriou P., Li J., Tornillo G., McCloy T., Barrow D., Droplet Microfluidics for Tumor Drug-Related Studies and Programmable Artificial Cells. Global Challenges, 2021, 5, 2000123.) /Pg 8 0 R /K [10] >> endobj 232 0 obj << /Type /StructElem /S /P /P 24 0 R /ActualText ([5] Lee J.M., Choi J.W., Ahrberg C.D. et al. Generation of tumor spheroids using a droplet-based microfluidic device for photothermal therapy. 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